Langerhans cell histiocytosis, a rare disorder that can damage tissue in the body.sarcoidosis, a disease in which abnormal levels of inflammatory cells gather in multiple organs of the body.leukemia and other types of cancer, including lymphoma and multiple myeloma.bacterial infections, such as tuberculosis, brucellosis, syphilis, and subacute bacterial endocarditis.chronic inflammatory diseases, such as inflammatory bowel disease.People with chronic infections tend to have elevated levels of monocytes, too.Ĭonditions that can lead to a spike in abs monocytes include: If you have an autoimmune disease, cells such as monocytes go after healthy cells in your body by mistake. Your body may make more monocytes once an infection is detected or if you have an autoimmune disease.
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